therapeutic expertise

Take back control of your clinical study.

Get a better understanding of your data.

Trust your trial with a partner that understands your specialty. From cardiovascular to respiratory, Quartesian experts have years of experience across a variety of different therapeutic areas. Take a look at our experience and areas of expertise:

Get thorough QT (TQT) clinical studies and early QT assessment within clinical pharmacology studies. Quartesian’s specialties include complex analyses and study designs, as well as a variety of cardiovascular indications.

Complex analyses and study designs include:

  • Mixed models for QTcF
  • Drug concertation
  • Williams 2 Square design for 4-way crossover studies

Other cardiovascular indications include:

  • Peripheral vascular occlusive disorder
  • Hyperlipidemia
  • Pericarditis
  • Venous thromboembolic disease

Get data management and statistical analysis and programming for a broad range of indications within the CNS therapeutic area. Quartesian’s experience includes specialties in:

  • Amyotrophic lateral sclerosis (ALS)
  • Lewy body dementia (LBD)
  • Alzheimer’s disease
  • Parkinson’s disease
  • Cerebral palsy
  • Multiple sclerosis
  • Epilepsy

Studies were in phases I to IV with a variety of analyses for endpoints, such as phenotype markers in early phase studies and outcomes from standard instruments for later phase studies.

Receive expert dermatological support from Quartesian — our core services have been contracted for eleven indications in the dermatology therapeutic area for major innovative and generic dermatology companies. We have noted proficiency in rater instruments and analysis, and our statistical expertise has been used to assess rater variability for global assessments. Quartesian’s specialties include:

  • Acne Vulgaris
  • Actinic Keratosis
  • Atopic Dermatitis
  • Facial Erythema Associated with Rosacea
  • Facial Rosacea
  • Head Lice
  • Impetigo
  • Lamellar Ichthyosis
  • Nasolabial Folds (NLF)
  • Papulopustular Rosacea
  • Plaque and Nail
  • Psoriasis
  • Plaque Psoriasis
  • Pruritus
  • Psoriasis
  • Rosacea
  • Scalp Psoriasis
  • Skin Aging
  • Skin Lesion
  • T-Cell Lymphoma
  • Tenia Pedis

Discover Quartesian’s expertise across musculoskeletal, arthritis, and analgesic areas. Our areas of expertise include:

  • Arthritis:
    • Osteoarthritis of the knee and hip
    • Measured joint pain, stiffness, and physical function using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
  • Musculoskeletal:
    • Acute painful spasm in lower back
    • Trauma
  • Analgesic
    • Third molar extraction
    • Bunionectomy
    • Measured via patient satisfaction surveys, visual analog scale (VAS), and sum of pain intensity differences (SPID) instruments
    • Validated data capture technologies such as EDC and ePRO

Take advantage of Quartesian’s library of eCRF pages specific to oncology studies, including multi-cycle study designs and controlled terminology for response rates and laboratory toxicity grades. Trust Quartesian with complex oncology study designs based on our experience in other complex models, such as Simon’s two stage study designs and adaptive study designs.

We apply statistical methodologies such as odds ratios, Cox proportional hazards model, and Kaplan-Meier for RECIST, survival rates, and bio-marker data. Take advantage of our machine learning (ML) algorithms to improve the consistency in the interpretation of image files from primary endpoint sources.

Quartesian’s experience expands across:

  • Relapsed Waldenström’s macroglobulinemia
  • Glioblastoma
  • Non-small cell lung cancer (NSCLC)
  • Circulating tumor cells (CTC)
  • Early stage t-cell lymphoma
  • Incurable, locally advanced or metastatic:
    • Breast cancer
    • Colorectal cancer
    • Pancreatic cancer
    • Bladder cancer
    • Ovarian cancer
Keep control of your data throughout your OB/GYN study with the help of Quartesian. We’re experts in:
 
  • Menstrual Disorders
  • Primary Hypothalamic Amenorrhea
  • Peritoneal and/ or Ovarian Endometriosis
  • Bacterial Vaginosis
  • Gynecologic Malignancies

Trust us with your ophthalmology study. Quartesian’s expertise includes:

  • Dry eye disease
  • Poor night vision
  • Cystinosis
  • Ocular inflammation
  • Uveitis
  • Corneal epithelial disorders
  • Dry age-related macular degeneration

We have experience in both early phase ethno-bridging studies and integrated summaries of safety (ISS). Continuous and discrete data from both general and ophthalmology-specific instruments were analyzed and summarized for both safety and efficacy.

Get valuable support with our psychiatric and behavioral expertise. Our psychiatric indications include:

  • Major depressive disorder
  • Bipolar disorder
  • Anxiety
  • Attention deficit hyperactivity disorder (ADHD)
  • Schizophrenia.

Our behavioral indications include:

  • Binge eating
  • Smoking cessation

Data capture technology, both EDC and ePRO/eCOA, were implanted and validated for instruments such as Montgomery-Asberg Depression Rating Scale (MADRS), Hamilton Depression Scale (HAM-D), and Columbia Suicide Severity Rating Scale (C-SSRS). We have also performed integrated summaries of safety (ISS) and QT prolongation analysis for schizophrenia studies.

Get a cost-effective model for studies in the rare disease space, where enrollment rates are slow and studies are conducted across multinational sites. Quartesian’s services are perfect for long-running studies with low rates of data capture.

Our cost-effective model has been used to rescue studies in rare indications such as:

  • Pelizaeus-Merzbacher Disease
  • Neuronal Ceroid-Lipofuscinoses

Master the data from your Renal study with Quartesian. We have expertise in: 

  • Impaired Renal Function
  • Renal Impairment

Take control of your respiratory study with Quartesian’s experience.

Quartesian has experience in:

  • Allergic Rhino-Conjunctivitis
  • Allergy
  • Asthma
  • Chronic Obstructive Pulmonary Disease (COPD)
  • Community-Acquired Bacterial Pneumonia
  • Cystic Fibrosis
  • Hepatic Impairment
  • Influenza-Viral Infection
  • Respiratory
  • Respiratory Syncytial Virus Infection​ (RSV)​

Our experts conducted a novel analysis within a COPD study to compare central reader spirometry data, investigating site reader spirometry data for forced expiratory volume (time) FEVt, to assess the effectiveness of the central reader. This measurement impacted the decision-making process for future studies.

Quartesian has supported the research for publication in a prestigious peer reviewed journal for a RSV study.

Put your mind at ease during your trauma clinical trial with Quartesian. We’re here to help keep you on track. Our areas of expertise are:
 
  • Wounds and Injuries
  • Abdominal Incisions Wound Healing
  • Knee Arthroplasty Wound Healing
  • Negative Pressure Wound Therapy System
Get seamless data for your vaccination trial with Quartesian’s data management and statistical analysis expertise.  Quartesian’s experience includes: 
 
  • Monovalent Virus-Like Particle (VLP) Venezuelan Equine Encephalitis Vaccine
  • Hookworm-Naïve

Ready to get started? Get in touch with our experts.

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